Infection Prevention Bundle

This is a series of four presentations describing infection risks and prevention practices for the premature neonate: infection risk and outcomes, strategies to reduce CLABSI (central line associated blood stream infection), skin care, and antibiotic stewardship programs in the NICU.


  1. Recall four factors that significantly increase the risk of infection in the small baby.
  2. List three examples of care delivery in the small baby that have been associated with a reduction in infection.
  3. Describe two co-morbidities associated with infection in the small baby.
  4. List three anatomic and functional differences in premature and ELBW infant skin.
  5. Give two key examples of care strategies to reduce the risk of CLABSI in the premature infant.
  6. Discuss two strategies to address extremely increased transepidermal water loss and evaporative heat loss in ELBW infants.
  7. Describe two preventative and two treatment techniques for skin breakdown due to the use of medical adhesives and skin disinfectants in ELBW infants.
  8. Identify potential for skin breakdown as portal of entry for infection, and discuss importance of early identification of bacterial and fungal microorganisms.
  9. Recall two risks of using antibiotics in the small baby.
  10. List two factors that can improve the accuracy of infection diagnosis in a small baby.
  11. Describe three strategies that have been used to reduce antibiotic exposure in the small baby.

Total CE 3.1

NCC Codes: NNP 2 = 1.3; NNP 3 = 1.1; NNP 4 = 0.75

NCC Codes: NIC 1 = 1.3; NIC 2 = 1.1; 3 = 0.75

NCC Codes: LRN 3 = 2.4; LRN 3 = 0.75

Rx possible = 0.75

*This presentation was included in the Small Baby Care Specialist® Program

Your Instructor

Linda Lefrak, Carolyn Lund, Alex Luton
Linda Lefrak, Carolyn Lund, Alex Luton

Linda Lefrak, Carolyn Lund, and Alex Luton are Neonatal Clinical Nurse Specialists who have practiced at several Children’s Hospitals. Some of their interests include neonatal nutrition, patient safety and quality improvement, infection risk reduction, and skin care. These NICU advanced practice nurses have provided extensive neonatal education across the country.

Course Curriculum

  Instructions & Handouts
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  Infection Risks & Outcomes
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  Infection Prevention:Central Line-Associated Blood Stream Infections (CLABSI)
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  Antibiotic Stewardship
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  Infection Prevention Bundle Suggested Reading
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Frequently Asked Questions

When does the course start and finish?
The course starts as soon as you enroll. You will have access to this course (videos) for two months. Please be sure to download lecture handouts for ongoing access to the content presented. You must complete and submit the Evaluation at the end of the course to receive CE.
How can I communicate any questions, comments, or feedback?
We would love to hear from you. Please e-mail us at: [email protected]

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